Chukwuma

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Posts by Chukwuma

Autism Spectrum Disorders and SSRIs

July 18, 2011 - 9:37 pm

Posted in Antidepressants, anxiety, autism, center for women's mental health, depression, pregnancy, Psychiatric Disorders During Pregnancy, SSRIs | No comments

It is now estimated that autism spectrum disorders (ASD) affect about 1% to 2% of the population.  Data derived from twin and sibling studies indicate that ASD is highly heritable.  While genetic factors clearly play an important role, other studies …

What is the Impact of Depression During Pregnancy?

July 12, 2011 - 8:32 pm

Posted in antenatal depression, center for women's mental health, depression, pregnancy, Pregnancy Outcomes, Psychiatric Disorders During Pregnancy | No comments

In a recent study by Gerardin and colleagues, the authors note that more research has been done to demonstrate the consequences of postpartum depression than depression during pregnancy (also called antenatal or prenatal depression).  Infants born to …

Serotonin Reuptake Inhibitors and Fertility (Part 2): What Can Basic Science Tell Us?

July 5, 2011 - 4:42 pm

Posted in Antidepressants, anxiety, basic sciences, depression, infertility, pregnancy, Pregnancy Outcomes, SSRIs, women's mental health | No comments

Serotonin (5-HT) is one of the neurotransmitters involved in mood regulation and has been implicated in the development of mood and anxiety disorders.  Serotonin transporters (SERT) facilitate the transfer of serotonin into neurons; serotonin reuptake…

Serotonin Reuptake Inhibitors and Fertility (Part 1): A Clinical Perspective

July 1, 2011 - 1:34 pm

Posted in Antidepressants, anxiety, infertility, Infertility and Mental Health, pregnancy, SSRIs, women's mental health | No comments

We previously reported that paroxetine, a selective serotonin reuptake inhibitor (SSRI), may affect sperm motility and may thus have a negative impact on male fertility.  Many women who are planning a pregnancy question whether SSRIs and other antidep…

Serotonin Reuptake Inhibitors and Fertility (Part 1): A Clinical Perspective

June 30, 2011 - 10:17 pm

Posted in Antidepressants, anxiety, depression, infertility, Infertility and Mental Health, IVF, pregnancy, SSRIs, women's mental health | No comments

We previously reported that paroxetine, a selective serotonin reuptake inhibitor (SSRI), may affect sperm motility and may thus have a negative impact on male fertility.  Many women who are planning a pregnancy question whether SSRIs and other antidep…

Generalized Anxiety in Pregnancy

June 21, 2011 - 1:16 pm

Posted in anxiety, pregnancy, Psychiatric Disorders During Pregnancy, women's mental health | No comments

Few studies have focused on anxiety disorders in the perinatal period. While various studies have measured levels of anxiety or distress during pregnancy, most studies have relied upon self-report questionnaires to assess for anxiety.  In contrast, fe…

Clinical Case: Should SSRIs Be Tapered Prior To Delivery?

June 13, 2011 - 5:26 pm

Posted in depression, Infants exposed to SSRIs, Neonatal Symptoms, pregnancy, SSRIs | No comments

Ms. T is a 33 year old woman with a history of recurrent depression who is 32 weeks    pregnant with her first pregnancy.  She has remained on her citalopram (Celexa) throughout pregnancy and has been well.  Her gynecologist has encouraged her to …

Postpartum Depression and Poor Sleep Quality Occur Together

June 6, 2011 - 4:52 pm

Posted in new mothers, postpartum depression, Postpartum Psychiatric Disorders, seel-deprived, sleep, women's mental health | No comments

In a new mother, sleep is disrupted by repeated awakenings of the infant, but hormonal factors also seem to play a role.  Immediately after childbirth, levels of the reproductive hormones, estrogen and progesterone, drop precipitously.  It is believe…

In Utero Exposure to Antipsychotics

May 17, 2011 - 8:47 pm

Posted in atypical antipsychotics, drugs during pregnancy, effects of antipsychotic medications on newborns, EPS, FDA, medication during pregnancy, National Pregnancy Registry for Atypical Antipsychotics, ObGyn News, pregnancy, Pregnancy Regsitry, psychiatric disorder during pregnancy, Psychiatric Disorders During Pregnancy, risk of medication during pregnancy, safety of medication during pregnancy, women's mental health | No comments

May 2011, ObGyn News, Lee S. Cohen, MD Reprinted with permission from Ob. Gyn. News Copyright by International Medical News Group, an Elsevier company   Previous columns on the reproductive safety of psychiatric medications have focused on the att…

Choice of Antidepressant May Affect Survival in Women on Tamoxifen for Breast Cancer

May 2, 2011 - 1:54 pm

Posted in Antidepressants, breast cancer, CYP2D6 inhibitors, selective estrogen receptor modulator, SSRI, Tamoxifen, women's mental health | No comments

Tamoxifen is a SERM (selective estrogen receptor modulator) used in women with breast cancer; it reduces the risk of relapse and improves overall survival.  Tamoxifen may also be used to reduce the risk of breast cancer in women at high risk for the d…

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