Antidepressants and pregnancy

Discontinuation of Antidepressants: Slower is Better

About half of all pregnancies are unplanned.  In this situation, many women who conceive while on psychotropic medications decide to abruptly stop their medications when they discover they are pregnant.  While this may seem like the safest option, in terms of protecting the developing fetus, we have data demonstrating high rates of relapse in women [...]

Should SSRIs Be Tapered Prior To Delivery?

Increased muscle tone, jitteriness, sleep disturbance, irritability, feeding problems, mild respiratory distress and myoclonus have been reported as symptoms of a potential neonatal distress syndrome related to exposure to SSRIs in late pregnancy.  The average duration of symptoms reported is 48 hours.  It is estimated that between 25-30% of SSRI-exposed infants are at risk for [...]

The Importance of Proper Dosing of Antidepressants during Pregnancy

Pregnancy and the postpartum period is a time of increased risk for depression.  Therefore, women who are treated with antidepressant medications must consider whether or not to stay on medication during pregnancy.  Despite reassuring data regarding the reproductive safety of various antidepressants, a woman may prefer not to continue medication during pregnancy due to concerns [...]

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