Trusted Information for Healthy Pregnancies
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Third-hand smoke a danger to babies, toddlers
Feb 10th
Add a new health threat to smoking: In addition to the harm caused by actually smoking and exposure to second-hand smoke, so-called third-hand smoke may also pose a threat, particularly to babies and toddlers.
A new study reveals that the residue of nicotine that lingers on surfaces can react with another chemical in the air to form potent carcinogens - chemicals linked to various cancers. While first-hand smoke is that inhaled directly by the smoker and second-hand is the smoke exhaled (and inhaled by others), third-hand smoke is the residue from second-hand smoke.
Anyone who has entered a confined space — a room, an elevator, a vehicle, etc. — where someone has recently been smoking, knows that the scent lingers for an extended period of time.
"The burning of tobacco releases nicotine in the form of a vapor that adsorbs strongly onto indoor surfaces, such as walls, floors, carpeting, drapes and furniture. Nicotine can persist on those materials for days, weeks and even months," said Hugo Destaillats, a chemist with Lawrence Berkeley National Laboratory in San Francisco, and one of the authors of the study.
Scientists have been aware for several years that tobacco smoke sort of sticks to surfaces where it can react with other chemicals. But reactions of residual smoke constituents with molecules in the air have been overlooked as a source of harmful pollutants, the researchers of the new study say.
"Our study shows that when this residual nicotine reacts with ambient nitrous acid it forms carcinogenic tobacco-specific nitrosamines or TSNAs," Destaillats said. "TSNAs are among the most broadly acting and potent carcinogens present in unburned tobacco and tobacco smoke."
Unvented gas appliances are the main source of nitrous acid indoors.
The researchers used cellulose as a model of indoor material, and exposed it to cigarette smoke. They then exposed it to a "high but reasonable" concentration of nitrous acid for three hours. The levels of newly formed TSNAs were 10 times higher after the nitrous acid exposure. The TSNAs also formed quickly, the researchers found.
"Given the rapid absorption and persistence of high levels of nicotine on indoor surfaces, including clothing and human skin, our findings indicate that third-hand smoke represents an unappreciated health hazard through dermal exposure, dust inhalation and ingestion," said lead author Mohamad Sleiman, also of Berkeley Lab.
Since most vehicle engines emit some nitrous acid that can infiltrate the passenger compartments, tests were also conducted on surfaces inside the truck of a heavy smoker, including the surface of a stainless steel glove compartment. These measurements also showed substantial levels of TSNAs.
Individuals are most likely exposed to these TSNAs through either inhalation of dust or the contact of skin with carpet or clothes, suggesting third-hand smoke might pose the greatest hazard to infants and toddlers.
And the study's findings, detailed in the Feb. 8 issue of the journal Proceedings of the National Academy of Sciences, indicate that opening a window or deploying a fan to ventilate the room while a cigarette burns does not eliminate the hazard of third-hand smoke.
"Smoking outside is better than smoking indoors but nicotine residues will stick to a smoker's skin and clothing," said study co-author Lara Gundel, also of Berkeley Lab. "Those residues follow a smoker back inside and get spread everywhere."
Source
Use of Acetaminophen in Pregnancy Associated With Increased Asthma Symptoms in Children
Feb 5th
Children who were exposed to acetaminophen prenatally were more likely to have asthma symptoms at age five in a study of 300 African-American and Dominican Republic children living in New York City. Building on prior research showing an association between both prenatal and postnatal acetaminophen and asthma, this is the first study to demonstrate a direct link between asthma and an ability to detoxify foreign substances in the body. The findings were published this week in the journal Thorax.
The study, conducted by the Columbia Center for Children's Environmental Health at Columbia University's Mailman School of Public Health, found that the relationship was stronger in children with a variant of a gene, glutathione S transferase, involved in detoxification of foreign substances. The variant is common among African-American and Hispanic populations. The results suggest that less efficient detoxification is a mechanism in the association between acetaminophen and asthma.
The researchers assessed the use of analgesics during pregnancy and found that 34 percent of mothers reported acetaminophen use during pregnancy, and 27 percent of children had wheeze, an asthma-related symptom. The children whose mothers had taken acetaminophen were more likely to wheeze, visit the emergency room for respiratory problems, and develop allergy symptoms, compared to those children whose mothers did not take acetaminophen. The risk increased with increasing number of days of prenatal acetaminophen use. The children in this study live in neighborhoods of New York City that have been the hardest hit by the asthma epidemic: Northern Manhattan and the South Bronx.
Acetaminophen use among children in the U.S. has increased substantially since the early 1980s and has become increasingly common among women during pregnancy so that most women in the U.S. take acetaminophen during pregnancy. This increase coincided with a doubling of the prevalence of asthma among children in the country between 1980 and 1995.
"These findings might provide an explanation for some of the increased asthma risk in minority communities and suggest caution in the use of acetaminophen in pregnancy," says Matthew S. Perzanowski, PhD, assistant professor of Environmental Health Sciences at the Mailman School of Public Health.
Reasons for prenatal acetaminophen use vary, but in this study population the observed associations with headaches suggest pain management as likely; however, other host factors that caused mothers to take acetaminophen and also cause asthma may explain their association. While infection is one such potential confounder, the Mailman School researchers found no association between the reported use of antibiotics and acetaminophen, and adjustment for antibiotic use during pregnancy did not affect the results.
According to the researchers, the prevalence of current wheeze diminished as the children aged, from 40 percent at age one year to 25 percent, 17 percent and 27 percent at ages two, three, and five, respectively. However, the association between prenatal acetaminophen exposure and current wheeze strengthened as the children aged.
The Columbia Center for Children's Environmental Health study adjusted relative risks for sex, race/ethnicity, birth order, maternal asthma, maternal hardship, exposure to environmental tobacco smoke, antibiotic use and postnatal acetaminophen use.
In a similar study conducted in the UK, the frequency of acetaminophen use during pregnancy and the magnitude of association in the UK study were similar to that in New York City.
Source
Prenatal Exposure to Flame-Retardant Compounds Affects Neurodevelopment of Young Children
Jan 27th
Prenatal exposure to ambient levels of flame retardant compounds called polybrominated diphenyl ethers (PBDEs) is associated with adverse neurodevelopmental effects in young children, according to researchers at the Columbia Center for Children's Environmental Health (CCCEH) at Columbia University's Mailman School of Public Health.
The study is online in Environmental Health Perspectives and will be released in the April 2010 print issue.
PBDEs are endocrine-disrupting chemicals and widely used flame-retardant compounds that are applied to a broad array of textiles and consumer products, including mattresses, upholstery, building materials, and electronic equipment. Because the compounds are additives rather than chemically bound to consumer products, they can be released into the environment. Human exposure may occur through dietary ingestion or through inhalation of dust containing PBDEs.
The researchers found that children with higher concentrations of PBDEs in their umbilical cord blood at birth scored lower on tests of mental and physical development between the ages of one and six. Developmental effects were particularly evident at four years of age, when verbal and full IQ scores were reduced 5.5 to 8.0 points for those with the highest prenatal exposures.
"The neurodevelopmental effects of prenatal exposure to PBDEs have not previously been studied among children in North America, where levels are typically higher than in Europe or Asia," said Julie Herbstman, PhD, first author on the paper and a research scientist in Environmental Health Sciences at the Mailman School of Public Health. "The findings are consistent with effects observed in animal studies and, if replicated in other North American populations, they could have important public health implications."
Frederica Perera, DrPh, professor of Environmental Health Sciences at the Mailman School, CCCEH Director, and coauthor added, "These findings are of potential concern, because IQ is a predictor of future educational performance; and the observed reductions in IQ scores are in the range seen with low level lead exposure." This research underscores the need for preventive policies to reduce toxic exposures occurring in utero."
The investigators controlled for factors that have previously been linked to neurodevelopment in other studies, including ethnicity, mother's IQ, child's sex, gestational age at birth, maternal age, prenatal exposure to environmental tobacco smoke, maternal education, material hardship, and breast feeding.
The study is part of a broader project examining the effects of chemicals released by the World Trade Center's destruction on pregnant women and their children. However, residential proximity to the World Trade Center site did not affect levels of PBDE exposure.
Source
Alcohol in Pregnancy has Variety of Possible Effects
Nov 23rd
A new study from Perth's Telethon Institute for Child Health Research has found evidence that the amount and timing of alcohol consumption in pregnancy affects child behavior in different ways.
The study has just been published online in the international journal Addiction.
Lead author Colleen O'Leary said the analysis was drawn from a random sample of more than 2000 mothers who completed a questionnaire three months after the baby's delivery, and were then followed up when the child was 2, 5 and 8 years of age.
"Mothers who reported what we would classify as heavy drinking in the first trimester of pregnancy were nearly three times as likely to report that their child suffered with anxiety and/or depression or somatic complaints," Ms O'Leary said.
“Those who drank moderately during that first trimester were twice as likely to report those types of behavioral issues for their child.
“Exposure to moderate or heavy levels of alcohol in late pregnancy increased the risk of aggressive types of behaviors in the child.
“This research suggests that both the timing and the intensity of alcohol exposure in the womb affect the type of behaviour problems expressed.”
In this study low levels of alcohol did not increase the risk of harm to the baby. However, the evidence clearly shows that the risk to the baby increases with increasing amounts consumed.
“It should also be noted that in this study moderate exposure is classified as drinking 3-4 standard drinks per occasion- that's about two normal glasses of wine-and no more than a bottle of wine drunk over a week.”
Heavy drinking included women who were drinking the equivalent of more than a bottle of wine per week.
“Not every child will be affected by prenatal exposure to alcohol. However it is important that women have this information about increased risk so that they can make informed decisions to give their child the best start to life,” Ms O'Leary said.
The National Health and Medical Research Council recommend that the safest choice for women who are pregnant or planning a pregnancy is to abstain from alcohol.
Source
ADHD Linked to Lead and Cigarette Exposure During Pregnancy
Nov 23rd
Children whose mothers smoked during pregnancy or who were exposed to lead have more than double the risk of having attention-deficit hyperactivity disorder (ADHD) as other children, new research shows.
And with exposure to both cigarettes and lead, the chances of having ADHD soared. Children whose mothers smoked during pregnancy and whose blood showed signs of lead exposure had eight times the risk of having ADHD.
"When you have both exposures, there is a synergistic effect," said study author Dr. Tanya Froehlich, a developmental and behavioral pediatric specialist and an assistant professor of pediatrics at Cincinnati Children's Hospital Medical Center.
The researchers concluded that about 38 percent of ADHD cases among children aged 8 to 15 in the United States may be caused by prenatal exposure to tobacco smoke, while 25 percent of ADHD cases are due to lead exposure, according to the study in the Nov. 23 online issue of Pediatrics.
Froehlich and her colleagues used data on 2,588 children aged 8 to 15 from around the nation who took part in the 2001-2004 National Health and Nutrition Examination Survey. Tobacco exposure was assessed by asking mothers if they smoked during pregnancy, while lead concentrations were measured by a blood test.
About 8.7 percent of children met the criteria for ADHD, which is marked by inattentiveness, difficulty focusing, impulsivity and hyperactivity, according to the study. The ADHD group included 16.8 percent of children whose mothers smoked during pregnancy, compared to 6.6 percent of children whose mothers did not smoke.
Lead exposure was divided into three groups: low, medium and high. About 5.2 percent of children who had the lowest lead blood levels had ADHD. About 9.1 percent of children in the middle range had ADHD, while 13.6 percent of children in the highest third had ADHD, the researchers found.
About 28.6 percent of children who were exposed to both prenatal smoking and who had higher blood lead concentrations had ADHD, Froehlich said.
Researchers did not find a strong link between exposure to secondhand cigarette smoke during childhood and ADHD.
Alarmingly, even children in the upper third had lead exposure levels lower than what the federal government considers "elevated." The U.S. Centers for Disease Control and Prevention considers levels of 10 micrograms per deciliter "actionable," Froehlich said. In the study, children in the upper third had blood lead levels that were 1.3 micrograms per deciliter or greater; children in the middle group had levels between 0.9 and 1.3 micrograms per deciliter.
About 250,000 U.S. children aged 1 to 5 have blood lead levels greater than 10 micrograms of lead per deciliter of blood, according to the CDC. Though blood lead levels have generally dropped in recent years, children, particularly those in poor, inner-city neighborhoods, may still be exposed to lead from peeling paint in old buildings. Leaded paint was banned for most residential uses in the United States in 1978.
Children may also ingest lead from old water pipes, soil and toys. In the last few years there have been multiple recalls, some by major toy manufacturers such as Mattel and Fisher-Price, of products manufactured in China that contained unsafe levels of lead.
"Lead is out there, and we need to take precautions, such as making sure we keep kids away from peeling paint and make sure they practice good hand washing before they eat if they are playing in the soil," Froehlich said.
In addition, good nutrition, including making sure children have adequate levels of iron and calcium, can also protect from lead exposure. Children with iron and calcium deficiencies absorb more lead than children with better diets, Froehlich explained.
Source
Toddler Helps Deliver Mom’s Baby
Nov 19th
Two-year-old Jeremiha Taylor can count to five, he's potty trained, oh, and he's a pro at delivering a baby. Seriously. On Friday, this little man was instrumental in the birth of his baby brother when his mom unexpectedly went into serious labor right on the living room sofa.
"I laid on the couch and he went and got a towel. He grabbed a towel on his own," mom Bobbye Favazza told The Commercial Appeal of Memphis. "It happened so fast. My water broke and the baby came two to three minutes later. I just pushed and he caught him."
When emergency personnel finally arrived Favazza was holding her baby, the cord still attached, and they waddled over to the front door to let them in. Ambulance workers cut the cord and transferred mom and baby to a local hospital, where they were discharged a short time later with no complications.
The birth of Favazza's fourth child, named Kamron Taylor, didn't go remotely as planned. She had a cesarean section scheduled for Dec. 6 — she delivered all her kids that way — and she did have some pains the night before Kamron's birth, but didn't think they were related to labor.
Instead, she woke up the morning of Friday the 13th and conducted family business as usual. But when her water broke just before 8:30 a.m. she knew she had little time to spare. She called her mother, who frantically called 911, and her 3-year-old panicked and sat on the couch and cried. Meanwhile, Jeremiha calmly sprang to action — and the rest is history.
"He's my little hero," Favazza declared. "It was like he knew what to do."
Perhaps she has an aspiring ob/gyn on her hands.
Source
Gift Ideas for the Geeky Mom and her Offspring
Nov 10th
Cuteness abounds at the thinkgeek webstore. Check out these adorable products for the geeky mom and her little ones, including a spill-proof bowl and Yoda backpack:
Free Weekend of Access to Caregiver Website
Nov 5th
Care.com is allowing free access this weekend to the premium services offered on their website in honor of National Family Caregiver Month. Find caregivers in your area, run background checks, and contact caregivers directly for free! You can find babysitters, nannies, senior caregivers, special needs caregivers, tutors, pet sitters and housekeepers. Visit their website to find out more! 